Allergic Contact Sensitizing Chemicals as Environmental Carcinogens
نویسندگان
چکیده
منابع مشابه
Allergic contact sensitizing chemicals as environmental carcinogens.
Chemicals that were bioassayed by the National Toxicology Program (NTP) and that also produce allergic dermatitis (ACD) in humans were evaluated for their tumorigenic characteristics. The impetus for the study was that most contact sensitizers, i.e., those that produce ACD, and genotoxic carcinogens are chemically similar in that they are electrophilic, thereby producing adducts on macromolecul...
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Correspondence : Mikio MIYATA at the above address. was given 2 days before the challenge, with variousconcentrationsbeingtested. Chloroform as trihalomethane in drinking water was administered for 2 days before the challenge. pDichlorobenzene was inhaled at one of several concentrations for 2 days before the challenge. The animals were sacrificed 30 min after the challenge by exsanguination un...
متن کاملScreening for skin-sensitizing allergens among patients with clinically suspected allergic contact dermatitis
OBJECTIVES To detect common skin-sensitizing agents among patients experiencing allergic contact dermatitis (ACD). Methods: This was a retrospective study of 152 patients with clinically suspected ACD who underwent patch testing in an allergy clinic at King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia between January 2012 and February 2015. Of these patients, only 74 (48%) patien...
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BACKGROUND No reports are available on allergic contact dermatitis in Saudi Arabia, although it seems to be a common skin problem. We attempted to explore certain clinical aspects in addition to the profile of sensitizing allergens in our area. As no standard panel for patch testing is available in our geographic region, we examined the suitability of the European Standard Series. METHODS Pat...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 1997
ISSN: 0091-6765
DOI: 10.2307/3433874